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Anti- tangata TIMP1 Antibody, Kiore Monoclonal

Whakaahuatanga Poto:

Te purenga Affinity-chromatography He momo momo Kaore i whakatauhia
Nga momo manaaki Kiore Tauhohenga momo Tangata
Taupānga Kimiluminescent Immunoassay (CLIA)

Taipitopito Hua

Tohu Hua

Taipitopito hua

Nga korero whanui
TIMP metallopeptidase inhibitor 1, e mohiotia ana ano ko TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating ngohe, TPA-S1TPA-induced protein Ko te aukati tissue o metalloproteinases 1, he aukati taiao o te matrix metalloproteinases (MMPs), he roopu peptidases. whai wāhi ki te whakahekenga o te kopu extracellular.Ka kitea te TIMP-1/TIMP1 i roto i nga kopa o te kopu me te pakeke.Ka kitea nga taumata teitei i roto i te wheua, te huhu, te ovary me te kōpū.Ko nga matatini me nga metalloproteinases me te kore e taea te whakakore i a raatau ma te herea ki o raatau konutea cofactor catalytic.Ko TIMP-1/TIMP1 te takawaenga i te erythropoiesis in vitro;engari, kaore i rite ki te IL-3, he momo-motuhake, he whakaihiihi i te tipu me te rereketanga o te tangata me te murine erythroid progenitors anake.I tua atu i tana mahi aukati ki te nuinga o nga MMP e mohiotia ana, ka taea e te pūmua te whakatairanga i te tipu o te pūtau i roto i te whānuitanga o nga momo pūtau, a he mahi anti-apoptotic ano pea.Ko te whakamaoritanga o tenei ira whakawaehere pūmua he tino kaha ki te whakautu ki te maha o nga cytokines me nga homoni.I tua atu, ko te korero mai i etahi engari ehara i te katoa o nga kromosom X kore mahi e tohu ana he polymorphic tenei ira ira i roto i nga wahine tangata.Ko tenei ira whakawaehere kei roto i te intron 6 o te ira synapsin I, ka tuhia ki te huarahi ke.Ko nga matatini me nga metalloproteinases me te kore e taea te whakakore i a raatau ma te herea ki o raatau konutea cofactor catalytic.E mohiotia ana a TIMP-1/TIMP1 hei mahi i runga i te MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 me MMP-16.

Āhuatanga

Tohutohu Takirua CLIA (Hopu-Hoki):
1D5-5 ~ 3G11-6
1D12-2 ~ 1G3-7
Maamaa >95% i whakatauhia e SDS-PAGE.
Whakatairanga Buffer PBS, pH7.4.
Rokiroki Whakaorangia i raro i nga tikanga parakore i te -20 ℃ ki te -80 ℃ ina whiwhi.
Ka tūtohu kia tohatohahia te pūmua ki nga rahinga iti mo te rokiroki pai.

Whakataurite Whakataetae

WHAKAMAHI (2)
WHAKAMAHI (1)

Nga korero ota

Ingoa Hua ngeru.Kao TT Clone
TIMP1 AB0034-1 1D5-5
AB0034-2 1D12-2
AB0034-3 1G3-7
AB0034-4 3G11-6

Tuhipoka: Ka taea e te Bioantibody te whakarite i nga rahinga mo o hiahia.

Nga korero

1.Barylski M, Kowalczyk E, Szadkowska I, et al.[Tukupa whakaahuru o te metalloproteinases[J].Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego, 2011, 30(178):246-8.

2.Hayakawa T , Yamashita K , Tanzawa K , et al.Ko te mahi whakatairanga tipu o te aukati kiko o te metalloproteinases-1 (TIMP-1) mo te whānuitanga o nga pūtau He take tipu hou pea i te serum [J].Pukapuka FEBS, 1992, 298.

3.Haider DG, Karin S, Gerhard P, et al.Ko te serum retinol-binding protein 4 ka whakahekehia i muri i te ngaronga o te taumaha i roto i nga kaupapa mate momo.[J].Journal of Clinical Endocrinology & Metabolism(3):1168-71.


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