Anti- tangata PIVKA -II Antibody, Kiore Monoclonal
Taipitopito hua
Nga korero whanui
Ko te Protein Na te Huaora K ngaro, te Antagonist-II ranei (PIVKA-II), e mohiotia ana ko Des-γ-carboxy-prothrombin (DCP), he ahua rereke o te prothrombin.Ko te tikanga, ko nga toenga waikawa glutamic 10 o te prothrombin (Glu) i roto i te rohe γ-carboxyglutamic acid (Gla) kei nga waahi 6, 7, 14, 16, 19, 20,25, 26, 29 me 32 he γ-carboxylated ki Gla e te huaora. -K whakawhirinaki γ- glutamyl carboxylase i roto i te ate ka huna ki roto plasma.I roto i nga turoro me te mate pukupuku hepatocellular (HCC), ka pakaru te γ-carboxylation o te prothrombin na reira ka hangaia te PIVKA-II hei utu mo te prothrombin.Ko te PIVKA-II ka kiia he tohu koiora pai mo te HCC.
Āhuatanga
| Tohutohu Takirua | CLIA (Hopu-Hoki): 1E5-1 ~ 1D6-10 1E5-1 ~ 1E6-7 |
| Maamaa | >95%, kua whakatauhia e SDS-PAGE |
| Whakatairanga Buffer | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
| Rokiroki | Whakaorangia i raro i nga tikanga parakore i te -20 ℃ ki te -80 ℃ ina whiwhi. Mo te rokiroki mo te wa roa, tena koa aliquot ka penapena.A ape i nga huringa whakatio me te rewharewha. |
Tātari Whakataurite
Nga korero ota
| Ingoa Hua | ngeru.Kao | TT Clone |
| PIVKA-Ⅱ | AB0009-1 | 1F4-5 |
| AB0009-2 | 1E5-1 | |
| AB0009-3 | 1D6-10 | |
| AB0009-4 | 1E6-7 |
Tuhipoka: Ka taea e te Bioantibody te whakarite i nga rahinga mo o hiahia.
Nga korero
1.Matsueda K , Yamamoto H , Yoshida Y , et al.Ko te mate pukupuku hepatoid o te pancreas e whakaputa ana i te pūmua na te kore huaora K, te antagonist II ranei (PIVKA-II) me te α-fetoprotein (AFP)[J].Journal of Gastroenterology, 2006, 41 (10): 1011-1019.
2.Viggiani, Valentina, Palombi,等.Ko te pūmua i puta mai i te kore huaora K, te antagonist-II ranei (PIVKA-II) i tino piki ake i roto i nga turoro mate pukupuku hepatocellular Italian.[J].Tutapa Scandinavian o Gastroenterology, 2016.
3.Simundic AM .Nga taunakitanga whaitake mo te tātari tauanga me te whakaaturanga raraunga i roto i te hautaka Biochemia Medica[J].Biochemia Medica, 2012, 22(1).
4.Tartaglione S, Pecorella I, Zarrillo SR, et al.Protein I Induced by Vitamin K Absence II (PIVKA-II) as a serological biomarker pea i roto i te mate pukupuku pancreatic: he rangahau pairati[J].Biochemia Medica, 2019, 29(2).
